Preliminary cannabis usage results

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Cannabis Research Database

1.   Research of cannabinoids regarding to all kind of diseases

Alzheimer’s Disease

Cannabinoids showed potent activity against a variety of methicillin-resistant Staphylococcus aureus (MRSA) and Streptococci:

• http://www.jneurosci.org/content/25/8/1904.short
• http://onlinelibrary.wiley.com/doi/10.1038/sj.bjp.0707446/full
• http://www.sciencedirect.com/science/article/pii/S0165614706002677
• http://molpharm.aspetjournals.org/content/79/6/964.short

Amyotrophic lateral sclerosis (ALS)

Research articles presenting results that are indicating that cannabinoids can have a delayed motor impairment and prolonged survival in experiments with mice:

• http://informahealthcare.com/doi/abs/10.1080/14660820310016813
• http://www.sciencedirect.com/science/article/pii/S0014299906005103
• http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.2006.04346.x/full

Analgesia (Pain reduction)

Research articles presenting results that are indicating that cannabinoids suppress nociceptive neurotransmission at the level of the spinal cord and the thalamus:

• http://www.ncbi.nlm.nih.gov/pubmed/21610490?dopt=Abstract
• http://www.ncbi.nlm.nih.gov/pubmed/10462067?dopt=Abstract=
• http://www.sciencedirect.com/science/article/pii/S0014299905010812
• http://www.nature.com/nature/journal/v395/n6700/abs/395381a0.html
• http://www.nature.com/nature/journal/v394/n6690/abs/394277a0.html
• http://www.ncbi.nlm.nih.gov/pubmed/15085199?dopt=Abstract
• http://www.ncbi.nlm.nih.gov/pubmed/9539680?dopt=Abstract
• http://www.ncbi.nlm.nih.gov/pubmed/11106791

2.   Research of cannabinoids regarding to CANCER

Brain (Glioma) cancer

Several research articles showing results how cannabinoids inhibit glioblastoma cell proliferation, expression and activity. The effects led to significant modulations of the cell cycle and induction of reactive oxygen species and apoptosis:

• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806496/
• http://www.nature.com/bjc/journal/v95/n2/abs/6603236a.html
• http://www.ncbi.nlm.nih.gov/pubmed/15313899
• http://www.ncbi.nlm.nih.gov/pubmed/23079154?dopt=Abstract
• http://www.ncbi.nlm.nih.gov/pubmed/11714882

Bladder cancer

Some interesting research articles describing a decrease of viability and apoptosis of bladder cancer cells by the influence of cannabinoids:

• http://www.sciencedirect.com/science/article/pii/S0090429510003663
• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878434/
• http://www.cps.org.tw/p/CJP/content/45/1/45133.pdf

Bone cancer

Some articles about the attenuated effect of cannabinoids on bone cancer:

• http://www.sciencedirect.com/science/article/pii/S000689930800807X
• http://www.sciencedirect.com/science/article/pii/S0024320510000755
• http://www.sciencedirect.com/science/article/pii/S0014299906013148

Breast cancer

Research articles showing how cannabinoids inhibits human breast cancer cell proliferation and invasion through differential modulation of the extracellular signal-regulated kinase and reactive oxygen species pathways, and eventually leading to down-regulation of metastasis expression and the activation of the intrinsic apoptotic pathway in breast cancer cells:

• http://www.ncbi.nlm.nih.gov/pubmed/20859676
• http://www.ncbi.nlm.nih.gov/pubmed/21566064?dopt=Abstract
• http://www.ncbi.nlm.nih.gov/pubmed/22776349
• http://www.ncbi.nlm.nih.gov/pubmed/15749859?dopt=Abstract

 

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